Present study was conducted during 2013-2014 in order to assess the weed flora of Darazinda, Frontier Region Dera Ismail Khan, Federally Administered Tribal Areas, Pakistan. In the present study 27 weed species belonging to 15 families were reported from the research area. Asteraceae family was dominated with 8 species followed by Papilionaceae (4 species). The family Poaceae was represented by three species and Polygonaceae was having two species, while the remaining families have only one species each. In life form the dominant was therophyte (17 species), followed by Geophyte (4 species), hemicryptophyte (3 species), chaemophytes (2 species) and one parasite. The leaf size spectra showed that nanophylls (13 species) were the dominant, followed by mesophyll (5 species), microphyll (4 species), leptophyll (2 species) and aphyllous with (2 species).