The effect of irrigation regimes and weed control treatments on quantitative and qualitative yield of sugar beet was studied at a private farm Joghatai (Razavi Khorasn province, Iran) in 2015. This experiment was carried out in a randomized complete block design with split arrangement having three replications. Factors were: Irrigation regimes (7 days interval (no stress) and 14 days interval (drought stress) as the main plot and weed control treatments as the sub plot. Weed control treatments consisted of (1) Weedy check, (2) hand-hoeing twice (3^rd and 6^th weeks after sugar beet emergence (WAE), (3) hand-hoeing thrice(3^rd, 6^th and 9^th WAE) (4) Betanal Progress Of (phenmedipham (9.2%) + desmedipham (7.2%) + ethofumesate (11.3%) @ 877 g a.i ha^-1  at 3 WAE  + one hoeing at 6^th WAE  (5) one hoeing at 3^rd WAE  + Betanal Progress Of application at 6^th WAE. The results showed that non-stress condition had more weed density, weed dry matter, root and sugar yield and sodium content and lower potassium content than drought stress treatment. Weed management had significantly affected on weed density, weed dry matter, root yield and sugar yield, so that weed infest had  more weed density (41.47%), and weed dry weight (61.47%) and less root yield (42.5%) and sugar yield (50.16%) than thrice hand-hoeing. All weed control treatments improved root yield compared with the unweeded check in both irrigation regime. However, the highest root and sugar yields were obtained by hand hoeing three times at 3^rd, 6^th and 9^th weeks after sugar beet emergence in non-stress condition.